Antigen in a Patient with SCID A Deletion in the Gene Encoding the CD45
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منابع مشابه
A deletion in the gene encoding the CD45 antigen in a patient with SCID.
SCID is a heterogeneous group of hereditary diseases. Mutations in the common gamma-chain (gamma(c)) of cytokine receptors, including those for IL-2, IL-4, IL-7, IL-9, and IL-15, are responsible for an X-linked form of the disease, while mutations of several other genes, including Janus-associated kinase-3, may cause autosomal recessive forms of SCID. We investigated the first SCID patient to b...
متن کاملA DELETION IN THE GENE ENCODING THE CD45 ANTIGEN IN A PATIENT WITH SCID Tchilan
Tchilan EZ, Wallace DL, Wells RS, Flower DR, Morgan G, Beverley PCL. J Immunol. 2001;166:1308–1313 Purpose of the Study. Defects in genes required for the development of T cells often underlie the primary immunodeficiency known as severe combined immunodeficiency (SCID). Many gene defects have been identified in SCID patients although the most common is the X-linked form of SCID that is attribu...
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تاریخ انتشار 2000